Milestones: Year 4
The Clumber Spaniel Health Foundation was incorporated in April of 2007. Its fiscal year runs from
January 1st through December 31st of each year. A 501(c)(3) public charity, in our forth year
we focused on the following areas.
COMMUNICATION & EDUCATION
RESEARCH PROJECTS 2010
- PDP1 International Database for Clumbers and Sussex Spaniels: This important list is
maintained on the CSHF website. Through voluntary submissions from owners and monthly
reports from the Animal Health Trust in the UK, a list of PDP1 status is compiled.
- The Piper Fund: These dedicated funds, initiated with a major gift from the
Kim and Cyrus Daboo family, are available to help reimburse owners for post mortem
necropsy examinations. Necropsy (canine autopsy) exams are very important to help us learn
more about disease conditions in Clumbers.
- E-newsletter: The Foundation continues to issue periodic e-newsletter editions,
to help inform and educate Clumber fanciers about CSHF research and fundraising efforts.
- Health Speakers: The CSHF was very pleased to help bring Dr. Mark Neff, a renowned
canine geneticist, to speak at the 2010 Vancouver, Washington, CSCA National. His informative
and entertaining talk was very well received.
- Clumber Spaniel Health Foundation website.
- The CSCA DNA Bank: The Clumber Spaniel Health Foundation manages the CSCA DNA bank,
under a Memorandum of Understanding with the CSCA. This extremely useful resource,
coupled with major advances in genomic technology, will enable researchers to help
unlock the mysteries of genetic diseases in both dogs and people. The CSHF invested in
salivary swabs in 2010. These swabs make it easy for Clumber owners to contribute to the
DNA Bank, and eliminate the need for a vet visit to have blood drawn. We anticipate
these swabs will encourage even greater participation in the bank, which currently
houses samples from over 700 Clumbers. The Foundation has underwritten the cost of the swabs,
and a board member has paid for the shipping to initial interested owners.
Owners are still responsible for the $15 per dog banking fee itself.
- Clumber Genome
The CSHF has provided DNA from one Clumber spaniel to T-Gen and the complete
genome has been mapped.
Hemangiosarcoma is a deadly form of cancer, which most frequently strikes in the
spleen in Clumbers. DNA from affected and unaffected, control Clumbers is part of a federally
funded research effort based at the Van Andel Research Institute in Michigan, and
T-Gen in Arizona. Hundreds of DNA samples from several breeds of dogs are being evaluated to
assess how the DNA of dogs who develop HSA varies from those dogs that do not.
- Immune Mediated Hemolytic Anemia
Formerly known as AutoImmune Hemolytic Anemia, IMHA is another deadly disease,
which affects Clumbers as well as many other breeds. IMHA causes a sudden onset,
life-threatening anemia, when the dog?s immune system starts to attack its own red blood cells.
While transfusions, steroids and other immunosuppressive drugs can save some affected dogs,
many others are lost to this disease. Dr. Lorna Kennedy at the University of Manchester, UK,
continues to investigate how and why the immune sys- tem goes awry in affected dogs.
The CSHF supported Dr. Kennedy?s research in 2010 via a contribution to the CSCA Donor
Advised Fund at the Canine Health Foundation. By pooling our dollars with those from other clubs,
we are able to help support larger research projects than we could fund alone.
- Intervertebral Disc Disease
Sadly, too many Clumber lovers know of a dog that has suffered lameness, paralysis
and/or euthanasia because of a bad back or a bad neck. Drs. Mark Neff and Nick Duesbery
at the Van Andel Research Institute are investigating this condition in Clumbers.
Forty DNA samples were sent to T-Gen in Phoenix for SNP analysis in December 2010,
along with the cancer samples.